Lil Buck Sinegal's career has spanned more than five decades. He's laid down over 300 recordings, having played and recorded with Clifton Chenier, Henry Gray, Rockin’ Dopsie, Buckwheat Zydeco, and many other blues artists, including Grammy-winning efforts with Paul Simon’s 1987 album Graceland.

On August 15, 2014, the WWOZ video team captured his performance of 'Down Home Blues' at the Blue Moon Saloon in Lafayette.